GSM1409239: RD2; Homo sapiens; RNA-Seq - SRA

SRX587765: GSM1409239: RD2; Homo sapiens; RNA-Seq
1 ILLUMINA (Illumina HiSeq 2000) run: 51.4M spots, 2.6G bases, 1.7Gb downloads

Submitted by: Gene Expression Omnibus (GEO)

Study: The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers

PRJNA252112 • SRP043078 • All experiments • All runs

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Our data demonstrated that Bcl6 directly binds and represses trafficking receptors S1pr1 and Grp183 by recruiting Hdac2 through the RD2 domain. Deregulation of these genes impairs B-cell migration and may contribute to the Germinal Center failure in Bcl6RD2MUT mice. Overall design: RNAseq was performed in endogenous BCL6-depleted OCI-LY1 cells rescued with either WT or RD mutant BCL6 (N=3 for each group).

Sample: RD2

SAMN02849459 • SRS633558 • All experiments • All runs

Organism: Homo sapiens

Library:

Instrument: Illumina HiSeq 2000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: SINGLE

Construction protocol: Cells were dissolved in Trizol and total RNA was extracted according to the Trizol protocol (Life Technologies, Cat. No. 15596-018). Libraries were constructed according to the Illumina Truseq RNA sample preparation guide.

Experiment attributes:

GEO Accession: GSM1409239

Links:

External link: GEO Sample GSM1409239

NCBI link: NCBI Entrez (gds)

Runs: 1 run, 51.4M spots, 2.6G bases, 1.7Gb

Run	# of Spots	# of Bases	Size	Published
SRR1373433	51,419,954	2.6G	1.7Gb	2014-09-17

ID:: 833520

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Sequence Read Archive

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